What medications should you not take Ginepristone with? Ginepristone tablets are an effective means of emergency contraception.

The pharmaceutical market offers a fairly large selection of drugs that provide emergency contraception, but almost all of them contain hormones in large dosages, which negatively affects a woman’s health. In fact, taking such a medicine is a hormonal attack; naturally, it does not go away without leaving a mark on your health. As unpleasant consequences, disruptions of the menstrual cycle are possible. One of the drugs that is non-hormonal in nature is, according to reviews, Ginepristone. It belongs to a group of drugs intended for emergency postcoital contraception. The drug is used to prevent unwanted pregnancy during unprotected intercourse. We will tell you about this drug, rules of administration and safety measures.

Application benefits

The main difference from other drugs of similar action is that the described drug is a non-hormonal drug. It has a different mechanism of action. To understand how the medicine works, you need to know how the process of conception occurs. In order for pregnancy to occur and develop normally in the future, the female body produces the hormone progesterone. It is thanks to it that the egg matures and leaves the follicle, and the endometrium changes, preparing for the implantation of a fertilized egg, and muscle tone decreases. Most emergency contraceptives block progesterone and ovarian function, which has negative consequences in the form of menstrual cycle disruptions. "Gynepristone" acts in a different way: the connection between hormones and receptors is blocked. In this case, interaction does not occur, which means conception is impossible. The uterine cavity does not accept the egg, it cannot gain a foothold in the endometrium, and increased muscle tone perceives it as a foreign object and helps it leave the body as quickly as possible. This is confirmed by reviews of gynecologists about the product “Ginepriston”.

Composition and release form

The drug is released in tablet form. Flat-cylindrical tablets of yellow or slightly greenish color, packed in blisters. The main active ingredient is mifepristone, and the auxiliary components are microcrystalline cellulose, sodium carboxymethyl starch and calcium stearate.

pharmachologic effect

"Ginepristone" is a synthetic antigestagenic drug prescribed to prevent unplanned pregnancy in case of unprotected sexual intercourse. The drug is indicated for use only as a last resort. To prevent conception, it is better to use other methods: medications or barriers. The active substance of the drug, entering the body before ovulation, prevents the egg from leaving the follicle. In this case, the follicle does not burst and the fertilized egg does not enter the uterine cavity, conception cannot occur. If the medication is taken after ovulation, the detachment process is accelerated, which makes it impossible for the fertilized egg to attach to the uterus. The price and reviews of Ginepristone are presented below.

Onset of action of the drug

The drug acts immediately after use: after two hours, maximum effectiveness is achieved. This indicator persists for the next twelve hours. Then the activity slowly decreases, and after three days complete neutralization and removal from the body occurs.

When does bleeding start?

Within a period of up to five days, scanty or heavy bleeding may appear (this depends on individual health parameters). The nature and duration of bleeding may vary; the norm is considered to be the presence of discharge for up to two weeks. If bleeding continues for 14 days and its intensity does not decrease, and there is also an increase in temperature, you should consult a doctor. The presence of bleeding is not obligatory; it may not exist at all. The hatching of the fertilized egg is almost impossible to track visually, since at this stage of development it is very small. In order to verify this, you need to do an ultrasound or conduct a pregnancy test at home. This is confirmed by reviews and instructions for the drug “Ginepristone”. The price depends on the region and pharmacy chain.

Indications for use

This drug is used by women of reproductive age as an emergency contraceptive measure when hormonal or barrier contraceptives do not give the desired result. This drug is not approved as a permanent means of protecting against unplanned pregnancy. Experts recommend using this drug no more than once over a period of time from 6 to 12 months. The price of Ginepriston, according to reviews, is quite high.

Contraindications

The described drug has a whole list of restrictions for use, therefore, before taking the pill, the patient should carefully read the instructions. Taking the drug is contraindicated in the following conditions:

• Insufficiency of adrenal function.
• Acute kidney or liver dysfunction.
• Chronic renal or liver failure.
• Long-term treatment with glucocorticoid drugs.
• Extragenital pathologies with aggravated course.
• Individual intolerance to the main active component of the drug, allergic reactions to mifepristone synonyms.

Reviews and consequences of taking Ginepristone are of interest to many. Varicose veins, severe lung diseases, chronic obstructive bronchitis, heart rhythm disturbances, chronic heart failure - for all these pathologies this drug is not prescribed or is prescribed with caution. In addition, the drug is contraindicated in patients with a history of hemodynamic disorders or arterial hypertension. This is confirmed by the instructions and reviews for Ginepriston.

Directions for use and dosage

Tablets are taken once: 1 pc. during the first three days after unprotected sexual intercourse. It should be remembered that the earlier you take the pill, the higher its effectiveness will be. The interval between eating and taking the tablet must be at least two hours, otherwise the therapeutic effectiveness of the medicine is significantly reduced. The drug can be taken on any day of the cycle in consultation with your doctor. If you suspect pregnancy (if the pregnancy is already long enough), the medicine should not be taken under any circumstances; you should consult a doctor. When breastfeeding, the use of the drug is possible only if the woman stops breastfeeding for a while and transfers the child to artificial nutrition. After taking the pill, feeding should not be resumed for two weeks.

Adverse reactions

According to reviews, while taking Ginepristone, side effects may occur in the form of:

• Nausea and vomiting.
• Severe headaches.
• Refusal to eat.
• Pain in the epigastric region.
• Bloody discharge from the genitals.
• Pain in the lower abdomen, cramps.
• Enlargement of the ovaries and tingling in them.
• Increased body temperature.
• Allergic reactions - urticaria, anaphylactic shock. This is confirmed by the instructions for use and reviews of Ginepristone.

Overdose

Taking more than one tablet at a time is not allowed. An independent increase in the recommended dosage or uncontrolled frequent use can lead to serious consequences:

• Heart rhythm disturbances.
• Severe pain in the lower abdomen.
• Liver and kidney failure.
• Adrenal gland dysfunction.

The appearance of any undesirable manifestations is a reason to immediately consult a doctor. In this case, symptomatic treatment is necessary. This is confirmed by reviews of doctors about Ginepristone.

Drug interactions

There are no described cases of interaction of this medication with other drugs in the specialized literature. If another drug has already been prescribed, but there is a need to take Gynepristone, you should first consult with your doctor. In addition, the tablets are not recommended to be taken together with non-steroidal anti-inflammatory drugs, as they can cause bleeding.

special instructions

As we have already said, Ginepriston (reviews are presented below) is not suitable as a permanent means of contraception. This is an emergency measure if the usual protective measures have failed. This drug is not able to protect against the transmission of sexually transmitted diseases and HIV infection, therefore, if you are not sure about your partner, you should use barrier methods of contraception. It should be recalled once again that the drug is not an abortifacient; if pregnancy has already occurred, the pills cannot be taken.

Storage conditions and price

Ginepristone is sold in pharmacies as prescribed by a doctor. The medicine must be stored at a temperature of no more than 25 degrees Celsius, in a dark place away from children. Shelf life is limited to three years from the date of issue. After the expiration date, the drug cannot be used. This drug costs from 400 to 500 rubles per tablet.

Instructions for use:

Clinical and pharmacological group

Ginepristone is a drug that belongs to the group of gestagens, and is also among the emergency contraceptives.

Release form, packaging and composition of Ginepristone

The analyzed product is available in flat-cylindrical tablets (1 tablet contains 10 mg of mifepristone), the color of which changes from light yellow to greenish.

The auxiliary components of Ginepristone include microcrystalline cellulose, calcium stearate, and sodium carboxymethyl starch.

In pharmacies it is sold in blister packs or cardboard boxes in quantities of 1-2 pcs. The drug is also sold in polymer jars, which also contain 1 or 2 tablets.

Pharmacological action of Ginepristone

The instructions for Ginepristone clearly indicate that this drug is intended for emergency prevention of pregnancy. The main active ingredient of this drug is mifepristone.

Mifepristone has a chemical structure that allows Ginepristone to be classified as a synthetic steroid (it should be noted that the adrenal glands are responsible for the production of steroid hormones found in the human body).

The action of Ginepristone is to block progesterone receptors (the main female hormone that is responsible for a successful and proper pregnancy). As a result of such processes, a poor environment for fertilization of the egg occurs in the uterus, as well as its impossible attachment to the walls of the uterus. The instructions for Ginepristone note that this drug also slows down the maturation of the egg (ovulation). To understand the pharmacological action of Ginepristone, it is necessary to remember what the ovulation process itself is. First of all, this is the release of an egg from a completely ready, mature ovarian follicle in order to prepare it for passage into the fallopian tube (oviduct). It is in the oviduct that fertilization occurs. Ovulation is a constant, monthly process that occurs every 19-45 days. Taking Ginepristone slows down the ovulation process. Also, unfavorable conditions for fertilization are created in the uterus, which are manifested in thickening of the mucus on the cervix, as well as changes in the functional layer of the uterus. Thus, Ginepristone for abortion is a very effective and reliable remedy.

Indications for use of Ginepristone

The instructions for Ginepristone contain detailed information that will tell you that this drug should be taken as a means of emergency contraception. Gynepristone will help protect a woman from unplanned pregnancy immediately after unprotected intercourse.

As stated in reviews of Ginepristone, in order to achieve the most positive result, you should take one tablet of the drug immediately after sexual intercourse or no later than 72 hours after it. Also in reviews of Ginepristone it is noted that the drug is best taken 2 hours before meals or 2 hours after it.

Contraindications

The instructions for Ginepristone indicate a number of contraindications, which you should definitely read before you start using this product.

1. The drug should not be taken if a woman has insufficient function of the adrenal glands, kidneys and liver.

2. Reviews of Ginepristone indicate undesirable use of the drug for those who suffer from chronic diseases or have been taking prednisolone, hydrocortisone or dexamethosone for a long time.

3. If any serious diseases are detected, Ginepristone is also not recommended to be taken.

4. Additional consultation with a specialist is also necessary in cases where a woman has problems with heart rhythm, if heart failure or a blood clotting disorder is detected.

5. Gynepristone does not need to be taken to terminate pregnancy if the woman previously took medications whose active substance was aimed at the blood clotting process.

6. Ginepristone should not be taken together with non-steroidal drugs, the action of which is aimed at eliminating the inflammation process (indomethacin, analgin, paracetamol, aspirin, etc.).

Having finished taking Ginepristone, breastfeeding should be continued only after 14 days.

Gynepristone dosage

Gynepristone should be taken orally 72 hours after completion of unprotected intercourse.

Ginepristone for abortion will work most effectively if you do not eat or drink 2 hours before taking the drug, and also refrain from eating for 2 hours after taking it.

Reviews of Ginepristone indicate that the drug does not affect the menstrual cycle, so you can take it whenever you want.

Side effects of Gynepristone

The most common side effects after taking Ginepristone are nausea, pain in the lower abdomen, dizziness, headache, vomiting, bleeding, skin rashes, fever, weakness, and menstrual irregularities.

One of the main functions of using various protections during sexual intercourse is to prevent unplanned pregnancy. But what to do if contraceptives were not at hand or they turned out to be of poor quality? In these cases, the solution may be so-called post-coital contraceptives, that is, drugs taken after unprotected intercourse. One of the most effective and proven drugs of this type is Ginepristone.

In contact with

Description of the drug and its benefits

Ginepristone is a synthetic steroid drug with a pronounced antigestagenic effect. Its essence lies in blocking the interaction of the hormone progesterone and the receptors that capture it. Due to this, the fertilized egg cannot attach to the endometrium and is soon excreted from the body. If the period of ovulation has not yet occurred, the drug prevents its onset.

Compared to other contraceptives of this kind, the drug has clear advantages. The main thing is the non-hormonal nature of the drug, which avoids problems with the endocrine system when using it. That is, the drug has a milder, but no less effective effect, which has been confirmed by practice.

Important! Another important detail is the absence of gestagenic activity, that is, the use of Gynepristone does not affect the ability to become pregnant in the future.

The pharmacokinetic characteristics of the contraceptive allow it to achieve maximum serum concentration within 2 hours when taking a single dose of 600 mg. At the same time, the connection with proteins is almost 100%. The half-life is about 18 hours. In particular, a decrease in concentration by half occurs between 12 and 72 hours after administration (depending on the organism). The remaining metabolites leave the body much faster - in 7-12 hours.

Indications for use and use

When and how to take postcoital contraceptive? The main indication for use of the drug is emergency contraception after unprotected sexual intercourse or in case of ineffectiveness/damage of other means (for example, perforation (rupture) of a condom). In these cases, to prevent unplanned pregnancy, it is necessary to take Ginepristone as soon as possible, no more than 3 days after coitus.

It is advisable to check the dose with your gynecologist, but in most cases one tablet (10 mg of mifepristone) is sufficient. To achieve the desired effect, it is recommended to avoid eating 2 hours before taking the tablet and for 2 hours after. The dosage can be increased depending on the phase of the cycle. The main reason for this is that ovulation has already occurred. The instructions for use indicate that the maximum safe dose that can be taken is 2 g, but such decisions should be made solely by the supervising physician.

The dosage of the drug should be checked with a gynecologist.

Contraindications and side effects

Like any drug, Ginepristone has a number of contraindications. Among them:

• renal failure;
• liver failure;
• long-term therapy with glucocorticosteroids;
• disruption of the endocrine system associated with the production of estrogen;
• chronic diseases of the genitourinary system;
• hypersensitivity to the components of the drug.

In addition, the contraceptive should be taken with caution if you have problems with the cardiovascular system, such as heart failure or arrhythmia. The medicine is taken under supervision in case of impaired blood clotting, diagnosed chronic obstructive pulmonary disease (COPD), or problems with blood pressure.

When using the drug Ginepristone, side effects may also occur. They are mainly caused by a violation of the dosage or dosage regimen. Such conditions include:

• migraine;
• elevated temperature (sometimes up to 39°C and above);
• general weakness;
• nausea, sometimes with vomiting;
• profuse bleeding from the genitals;
• hives;
• menstrual irregularities;
• pain and other manifestations of discomfort in the pelvic area.

Important! When using Gynepristone during lactation it is necessary stop breastfeeding for a period of at least 2 weeks.

Overdose may cause disruption of the adrenal glands. In these cases, mandatory consultation with a specialist and symptomatic treatment are necessary.

Advantages of the drug

Features of use and storage

How often can I use the drug? The use of Gynepristone as postcoital contraception on an ongoing basis is strictly not recommended. Otherwise, the effectiveness of its action is reduced, initially amounting to 98.8%. In addition, the development of adrenal insufficiency and various liver and kidney dysfunctions may be a consequence. During use, driving vehicles and other machinery is permitted.

Important! The drug is used only as a solution to the issue of unwanted pregnancy - it does not function as a barrier to sexually transmitted diseases.

If we talk about the compatibility of the drug with other drugs, the simultaneous use of Ginepristone and non-steroidal anti-inflammatory drugs (NSAIDs, ibuprofen, diclofenac) is not recommended. If such a “neighborhood” is necessary, the dose of NSAIDs must be adjusted. One of the burning questions for female representatives is: “Is Gynepristone sold by prescription or not?” Yes, purchase of the drug requires a prescription, so you should ensure its availability in advance.

The drug belongs to list A. It should be stored in a dark, dry place, at a temperature not exceeding 30° C. The maximum shelf life is 36 months.

To purchase the drug, you must take a prescription from a doctor.

Analogues and comparison with them

Below is a list of the most common analogues of Ginepristone and their relative comparison with it:

1. Agesta. It is a complete analogue, that is, it has an absolutely identical composition. Consequently, it has all the advantages and disadvantages of the drug in question. It also loses effectiveness with constant use. The average cost is 130 rubles.
2. Ginestril. The drug has a wider list of side effects. The advantage is the extended spectrum of action - it is often prescribed as prevention of uterine leiomyomas, one of the common causes of infertility. The average cost is 5620 rubles.
3. Genale. The effect of this drug, when used regularly, is much more serious than the corresponding characteristic of Ginepristone. If pregnancy occurs while using it, there is a high risk of having a child with congenital pathologies. The average cost is 300 rubles.
4. Miropriston. It is considered one of the most effective postcoital contraceptives. Under its influence, a sharp contraction of the uterus occurs during the day, which leads to rejection of the fertilized egg. It is not commercially available and is prescribed exclusively by the supervising physician. It has a considerable list of side effects. The average cost is 2200 rubles.
5. Mifeprex. The drug is taken only in the presence of a doctor in a medical facility, where the woman spends another 2 hours under observation. The list of contraindications is wider, but it is possible to use it much later than within 72 hours after sexual intercourse. It is, in fact, a method of pharmaceutical abortion, therefore it can only be purchased with a doctor’s prescription. The average cost is 1200 rubles.
6. Mytholian. It is almost a complete analogue of Mifeprex, therefore it has a similar type of effect and characteristics. Its use is permitted up to one and a half months after the last menstruation. Distributed in pharmacies only upon presentation of a prescription. The average cost is 1200 rubles.
7. Mifotab. Another analogue similar to Mifeprex. Possessing an almost identical composition, it has reduced efficiency(about 80%) and a greater number of contraindications. Available only by prescription. The average price is 2000 rubles.
8. Pencrofton. In many ways similar to Ginepriston. It has the same efficiency and similar characteristics. The average cost is 3000 rubles.

Ginepristone, like many of the drugs listed, is sold by prescription at an average price of 430 rubles.

Ginepristone is available in the form of 10 mg tablets, in cardboard packages, one or two tablets.

The drug contains one active ingredient – ​​mifepristone. Excipients are:

• sodium carboxymethyl starch;
• calcium stearate.

Mifeprestone is a synthetic antagonist of the hormone progesterone, which is also responsible for creating the conditions for pregnancy. Gynepristone blocks the synthesis of this hormone. It also blocks the action of glucocorticoids.

Increases the contractile activity of the uterus, promoting the rejection of the fertilized egg.

Sometimes the drug is prescribed simultaneously with prostaglandin, which mutually enhances its effectiveness.

In addition, the drug is able to inhibit the development of uterine tumors and fibroids.

Indications for use of Ginepristone

The instructions for Ginepristone say that the indications for its use are:

• medical termination of pregnancy in the early stages (up to the 42nd day of delay);
• emergency contraception after unprotected sexual intercourse (up to 72 hours after it);
• therapy for uterine fibroids up to the 12th week of pregnancy;
• preparation for childbirth during full-term pregnancy.

Contraindications

Contraindications to the use of Ginepristone are:

• violation of hemostasis;
• anemia;
• treatment with anticoagulants;
• severe external genital pathology;
• inflammatory diseases of the genital organs;
• presence of a scar on the uterus;
• porphyria;
• acute and chronic renal or liver failure;
• long-term treatment with glucocorticoids;
• dysfunction of the adrenal glands;
• hypersensitivity to the components of the drug.

A relative contraindication to the use of Ginepristone is smoking over the age of 35 without prior consultation with a doctor.

In addition, there are a number of specific contraindications that are taken into account only when treating certain conditions or diseases.

When treating uterine fibroids, contraindications for use are:

• pregnancy;
• lactation;
• submucous location of myoma nodes;
• ovarian tumors;
• endometrial hyperplasia;
• the size of fibroids exceeding 12 weeks of pregnancy.

When preparing and inducing labor, contraindications to the use of the drug are:

• uterine fibroids;
• premature or post-term pregnancy;
• eclampsia and preeclampsia;
• severe gestosis.

When terminating pregnancy, contraindications to the use of Ginepristone are:

• uterine fibroids;
• pregnancy that occurred while taking or after recent discontinuation of oral and intrauterine hormonal contraceptives;
• pregnancy not confirmed by research, or exceeding 42 weeks;
• ectopic pregnancy or suspicion of it.

Take with caution and under medical supervision:

• for cardiovascular diseases and predisposition to them;
• for bronchial asthma and chronic obstructive pulmonary diseases;

Method of administration and dosage of Ginepristone

The instructions for Ginepristone say that it is taken orally according to the following schemes:

For the treatment of uterine fibroids, 50 mg of the drug is taken once, for a course of 3 months.

For emergency postcoital contraception, take 10 mg of the drug (one tablet) in the first 72 hours after unprotected intercourse, regardless of the phase of the menstrual cycle, two hours before eating. You should also refrain from eating for two hours after taking Ginepristone.

To prepare for labor and induce it, take 200 mg of the drug at once, in the presence of a doctor. A day later, take the same dose again.

To terminate a pregnancy, 600 mg of the drug is taken at once, in the presence of a doctor. Misoprostol is taken at the same time. You must remain under medical supervision for two hours after taking it. After two days, ultrasound control is carried out. In case of incomplete abortion or ongoing pregnancy, the vacuum aspiration method is used.

In case of overdose, the development of acute adrenal insufficiency is observed.

Side effects of Gynepristone

Among the nonspecific side effects of Gynepristone are the following:

• skin rashes;
• temperature increase;
• diarrhea;
• vomiting and nausea;
• dizziness;
• headache;
• weakness;
• feeling of discomfort in the lower abdomen.

In addition to this, when treated with Ginepristone together with misoprostol, the following side effects occur:

• leucorrhoea;
• fainting conditions;
• decrease in hemoglobin;
• anemia;
• anxiety;
• leg pain;
• asthenia;
• insomnia;
• indigestion;
• vaginitis

When interrupting a pregnancy procedure with Ginepristone, the following may additionally occur:

• exacerbation of infections of the uterus and urinary tract;
• inflammation of the uterus and appendages;
• lower abdominal pain;
• bleeding.

Among other specific side effects of Gynepristone:

• cycle disorders, amenorrhea (in the treatment of fibroids);
• cycle disorders and bleeding from the genital tract (with emergency contraception).

special instructions

Dispensed by prescription.

Simultaneous use of non-steroidal anti-inflammatory drugs with Ginepristone causes a weakening of its effect.

Taking the drug to terminate a pregnancy or induce labor is possible only in a hospital, as there is a high probability of heavy bleeding requiring immediate surgical intervention.

If pregnancy continues after taking Ginepristone, it is necessary to terminate it surgically, since the drug causes fetal malformations.

Does not protect against sexually transmitted diseases.

Analogues of Ginepriston

Among the exact analogues of the drug: Agesta, Pencrofton, Ginesteril, Zhenale, Mifegin and some others.

Terms and conditions of storage

Ginepristone is stored at a temperature not exceeding 30 degrees Celsius, out of the reach of children.

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Ginepristone is a steroidal and antigestogenic medicine that is used to terminate pregnancy in the early stages, but not more than forty-two days of amenorrhea.
Three weeks of pregnancy is the period when, after using this drug, its effectiveness reaches almost one hundred percent.

But if it is amenorrhea, which is more than forty-nine days, after the first day of the last menstruation, then the effectiveness of the drug will significantly deteriorate.
And like any medical abortion, it should only be carried out in a clinic, under the supervision of a gynecologist. But there are cases when, after a medical termination of pregnancy, the fetus does not die, and an incomplete abortion occurs. In such cases, the doctor informs the patient that the pregnancy still needs to be terminated, since the child in this case may be born with defects, sometimes even incompatible with life.

Instructions for use

The package of the drug "Ginepristone" usually contains one or two tablets. These pills prevent progesterone receptors from activating and disrupt its regulation regarding the attachment of a fertilized egg. Also, this drug interferes with the normal course of ovulation, which in the absence of progesterone slows down greatly. Also, mucus begins to thicken in the cervix, which creates an unfavorable environment for the continuation of pregnancy.

The procedure for terminating pregnancy with gynepristone

This technology involves a three-time visit to the doctor.

1. An hour before visiting the gynecologist, you need to have a light breakfast, but nothing heavy. And already directly at the doctor’s office, the pregnant woman drinks three tablets of gynepristone. The dose of each of them is two hundred milligrams. After the procedure for taking the pills, the patient remains within the clinic for several more hours so that the doctor can monitor the woman’s tolerance to the drug. In many women, spotting can be detected on the same day, but only five percent have a final abortion.
2. Two days later, the woman comes to the doctor again. Under the doctor's supervision, she takes two more misoprostol tablets. Each of them is equal to 200 mcg. After this drug, the woman remains under observation for three or more hours. While the woman is in the clinic, she should already start bleeding, but if this is not observed, the gynecologist gives the woman two more tablets to drink. The duration of bleeding largely depends on how far into pregnancy the woman is. If we are talking about a period of four weeks of pregnancy, then often the abortion occurs like normal menstruation. But the discharge can last from one to two weeks. But if we are talking about late pregnancy, then bleeding can be heavy.
3. And the third visit to the doctor must be made two weeks after the woman took Misoprostol. This technique is needed in order to exclude the possibility of continuing the pregnancy, or detecting an incomplete abortion. This examination is extremely important throughout the course of abortion, so you should not neglect it, as this may be fraught with consequences.

Side effects of Gynepristone

• Gag reflexes, cramps in the lower abdomen, diarrhea, lethargy, fatigue, migraines, dizziness.
• Increased body temperature, severe and prolonged bleeding, chills.

Therefore, if you definitely decide to end your pregnancy, do not expose your body to severe, possible consequences, and immediately consult a doctor, under whose strict guidance you will quickly recover.