Fervex (powder for solution, rhinitis tablets) - instructions for use, reviews, analogues, side effects of the drug and indications for the treatment of colds, sore throat, dry cough in adults and children. Compound
With its help you can relieve fever and body aches.
Fervex composition and dosage form
Fervex is available in powder form for dilution. It is packaged in laminated sachets of 4.95 g (single dose).
One sachet contains 500 mg, 200 mg of ascorbic acid () and 25 mg of pheniramine maleate.
Additional ingredients give the finished drink a pleasant taste and aroma.
In what cases can Fervex be taken?
This medicine is prescribed for the symptomatic treatment of colds and acute respiratory viral infections. It does not affect the cause of the disease and does not speed up the healing process.
Fervex eliminates the following symptoms:
Who is Fervex contraindicated for?
The drug should not be taken by persons with individual hypersensitivity to one or more active and auxiliary substances in order to avoid allergic reactions.
Diseases and pathological conditions for which the drug is contraindicated:
- severe functional renal failure;
- damage to the coronary vessels;
- hypertonic disease;
- portal hypertension;
- closed angle;
- “aspirin triad” (+ intolerance to salicylates and other NSAIDs + nasal polyposis);
- active liver diseases (including viral, alcoholic and);
- erosions and ulcers of the gastrointestinal tract (in the acute phase);
Fervex is not prescribed to children and adolescents under 15 years of age!
The powder from one sachet is dissolved in 200 ml of warm boiled water. The prepared solution is drunk 3-4 times a day, maintaining 4-hour time intervals.
The duration of use as an antipyretic should not exceed 3 consecutive days. To relieve pain, Fervex can be taken for 5 days. If there is a need to extend therapy, you should consult your local physician. Long-term use of drugs containing paracetamol requires monitoring of peripheral blood patterns and monitoring of liver functions.
Side effects
The vast majority of patients tolerate Fervex well.
If you are intolerant to the components of the drug, allergic reactions in the form of skin itching, bronchospasm and angioedema are possible. In particularly severe cases, it is possible posing a serious threat to life.
In rare cases, the following side effects have been observed:
- psychomotor agitation;
- dyspeptic disorders;
- feeling
- dysuria;
- epigastric pain (in the projection of the stomach);
- blurred vision near;
With long-term uncontrolled treatment with high doses, interstitial and hepatonecrosis may develop. A blood test may show anemia, leukocytopenia and thrombocytopenia.
Overdose
In case of overdose, signs of paracetamol poisoning develop. The danger is represented by a dose ≥ 10 g. Even with good general condition, you need to call an ambulance.
Clinical signs overdose:
- (sharp decrease or lack of appetite);
- abdominal pain;
- pale skin;
- sweating;
- worsening blood clotting.
Large doses cause progressive encephalopathy. Collapse, coma are possible, and in especially severe cases, death cannot be ruled out.
Within 2 hours you need to rinse your stomach and take (for example -). In the first 8-9 hours, the introduction of a specific antidote is required - methionine. After 12 hours, IV injections of N-acetylcysteine are needed for detoxification. Overdose is grounds for hospitalization; In the hospital, if indicated, intensive therapy and hemodialysis are carried out.
pharmachologic effect
Paracetamol blocks the enzyme cyclooxygenase in the central nervous system, thereby reducing the biosynthesis of mediators of pain and inflammation - prostacyclins and prostaglandins. The antipyretic effect is due to the direct influence of the substance on the hypothalamic thermoregulation center, the excitability of which decreases.
Ascorbic acid is a powerful antioxidant and immunomodulator. It is directly involved in the metabolism of carbohydrates and stimulates regeneration processes. The body's need for vitamin C increases sharply during infectious diseases. Its intake helps to increase nonspecific immunity.
Pheniramine is an antihistamine. It reduces swelling of the mucous membranes and reduces vascular permeability, thereby facilitating nasal breathing and reducing rhinorrhea.
Interaction with other drugs
Even with the consumption of relatively small doses of paracetamol (5 g), a hepatotoxic effect cannot be excluded if the patient takes Rifampicin, antiepileptic drugs (Carbamazepine) and antipsychotic drugs(Phenytoin).
Glucocorticosteroid hormones increase the risk of developing glaucoma.
It is important to exclude the parallel use of Fervex with tricyclic.
Efficiency indirect anticoagulants and antiplatelet agents in combination with paracetamol increases, and uricosuric drugs– decreases.
This active substance enhances the sedative effect of antiallergic drugs. () drugs.
During therapy should not be taken anxiolytics and NSAIDs(especially those containing paracetamol).
Fervex during pregnancy
INI andIn the third trimester, this drug is strictly contraindicated, and inII, it should be used with great caution and only after consultation with the doctor managing the pregnancy. If it is necessary to take Fervex during lactation, the baby must be temporarily transferred to artificial milk formula.
Additionally
During treatment, you should refrain from drinking alcohol, since ethyl alcohol increases the risk of developing severe pancreatitis and hepatonecrosis.
Theraflu is one of the most common Swiss drugs that is used for viral infections. This category includes a range of products in powder, tablet, spray and syrup form. In some cases, it becomes necessary to select an analogue of Theraflu. This is best done under the guidance of a doctor.
Characteristics of the drug
Before choosing analogs that are cheaper than Theraflu, it is worth analyzing the composition of this drug. There are several types of this medicine on sale, but they all contain paracetamol and phenylephrine. At the same time, Theraflu for colds and flu contains ascorbic acid. Also, some products from the line contain pheniramine.
This medicinal composition successfully copes with nasal congestion, general weakness, and headaches. It can also be used to eliminate fever and other symptoms of ARVI.
The action of the product is due to its composition:
Pheniramine has a sedative effect. Therefore, taking Theraflu at night improves sleep, which is often disturbed when infected with viral infections.
The ingredients of the medicine are absorbed by the body quite quickly. In this case, the maximum therapeutic effect occurs within 1 hour. The drug lasts approximately 5-6 hours.
The main indications for use of the drug include symptomatic treatment of pathologies of an inflammatory and infectious nature. This substance perfectly helps with fever, chills, and nasal congestion. It can also help eliminate headaches, muscle discomfort, and rhinitis.
Theraflu is prescribed to adults and children over 12 years of age. To cope with ARVI, the contents of the sachet should be mixed with a glass of hot water. The product must be consumed hot. The maximum permissible daily volume is 3 sachets. Between taking the product you need to leave a gap of 5-6 hours. Therapy without consultation with a specialist is permissible for a maximum of 5 days. If the patient's condition does not improve, you should consult a therapist.
List of cheap analogues of Theraflu
In some cases, it becomes necessary to select a replacement drug. The price of Theraflu analogues may vary. Therefore, when choosing a treatment, you need to take into account several parameters at once - composition, dosage, volume.
Below is a list of Theraflu analogues:
- antigripin - available in the form of effervescent tablets and costs about 300 rubles;
- rinicold hotmix - powder will cost about 250 rubles;
- stopgripan - the product is produced in powder form, it costs about 270 rubles;
- maxicold rhino - the product will cost about 200 rubles;
- upsarin UPSA - effervescent tablets will cost approximately 200 rubles;
- influenza flu - this powder costs about 230 rubles;
- coldact flu plus - produced in the form of capsules, which cost about 200 rubles;
- rinzasip - produced in powder form for 330 rubles;
- colds - the price of the powder is 150 rubles;
- coldrex hotrem lemon - this product in powder form costs approximately 330 rubles;
- Fervex UPSA - will cost about 300 rubles.
The listed analogues of Theraflu powder are not much cheaper - the difference in price does not exceed 20-30 rubles. More expensive drugs with a similar effect include antiflu in dosage form powder No. 5 for 200 rubles and Anvimax, which costs about 360 rubles.
The composition of Theraflu analogues is almost the same. Thus, fluflu, stopgripan include the same active ingredients - ascorbic acid, paracetamol, pheniramine. The only difference is the volume of active components.
In some cases, it is necessary to select analogues of Theraflu spray. These include drugs such as Anzibel, Novosept Forte, anti-angin, etc.
Theraflu or Anvimax - which is better?
When comparing these drugs, you can notice significant differences in composition. Common active ingredients include paracetamol and ascorbic acid. In this case, Theraflu additionally includes phenylephrine and pheniramine. At the same time, Anvimax contains calcium gluconate and rutoside trihydrate. This substance contains rimantadine hydrochloride and chloratadine monohydrate.
Due to this, the list of effects of Anvimax is significantly expanded. Just like Theraflu, this substance helps reduce temperature, relieve pain and provides an antihistamine effect. In addition, Anvimax has an antiviral effect and is distinguished by interferonogenic and angioprotective characteristics. In other words, Anvimax belongs to the category of etiotropic drugs, which, in addition to symptomatic action, help cope with the causes of ARVI.
These substances have similar indications and contraindications. The instructions for the analogue Theraflu contain the same list of side effects. The prices of these funds are also almost the same. Only minor differences are possible, which usually do not exceed 50 rubles.
In addition, Anvimax is a Russian analogue of Theraflu. The only drawback of this remedy is the impossibility of treating children and adolescents. In any case, this substance should only be prescribed by a doctor.
Theraflu or Fervex
When choosing Fervex or Theraflu, it is worth considering that the products have almost identical composition. Theraflu also contains phenylephrine. The differences lie in age restrictions. Thus, Fervex can be taken from the age of 15, while Theraflu can be taken from the age of 12.
The remaining criteria, such as indications, features of use, contraindications, are the same for these products. At the same time, the instructions for Fervex note that it cannot be used in the 1st and 3rd trimesters of pregnancy. This means that the product can be used during the 2nd trimester. However, this is allowed only under the supervision of a doctor.
The cost of Fervex is slightly lower - about 50 rubles. This can be included in the list of its advantages.
Theraflu or antigrippin - what to choose
Both medications include paracetamol and vitamin C. However, their other components differ. In addition, these substances have different age restrictions. Thus, antigrippin can be used from the age of 15, while Theraflu can be used as early as 12 years of age.
The cost of medications does not differ much. Antigrippin is about 60 rubles cheaper. It also has a more convenient method of application - it can be mixed with warm water and not consumed as a hot drink. The fact is that not all people can drink hot liquid. Antigrippin can be taken in a more convenient form.
According to other criteria, these funds do not have any special differences. When choosing a specific drug, you should pay attention to age, cost and ease of use.
Theraflu or stopgripan
The drug stopgripan is also available in powder form. The product is produced by an Indian company. This is an excellent solution for those looking for a cheaper alternative to Theraflu. This product has a similar composition, since it contains paracetamol, vitamin C, phenylephrine and pheniramine. The amounts of these substances are also the same.
The main difference between Stopgripan and the Swiss drug Theraflu is the composition of the auxiliary ingredients. People who like the taste of blackcurrant prefer to choose stopgripan. The composition of flavors and dyes is also different.
If an increased level of paracetamol is required, you should choose the drug stopgripan forte. It contains 650 mg of this substance. In the Theraflu line of drugs, this amount contains a product marked “extra”. However, stopgripan still has a slight difference - vitamin C in the amount of 50 mg is also added to its composition.
Theraflu or flufluflu - what to choose
These substances have the same set of active ingredients, which allows us to conclude that they are structural analogues. However, there are some minor differences. Thus, Theraflu has a lemon flavor, while Influenzaflu is produced with the aroma of other fruits and berries - in particular, currants and raspberries. You can also find a product with the scent of cranberries and strawberries on sale.
This Russian manufacturer also has the drug influenzaflu extra in its arsenal. It contains double the amount of paracetamol. Like stopgripan, this substance also contains vitamin C.
Theraflu or Maxicold
This product is available in powder form. Its composition is completely identical to the active components of Theraflu. Maxicold includes paracetamol, pheniramine, phenylephrine. It also contains ascorbic acid. Thanks to the presence of aromatic and nutritional additives, taking the product is very pleasant. This substance has the taste of orange, lemon or raspberry.
In addition, the manufacturer offers Maxicold with a high content of paracetamol and vitamin C. It contains 750 mg of paracetamol, as well as 60 mg of vitamin C. In addition, the drug contains 10 mg of phenylephrine. However, pheniramine is not present in this medicine.
Theraflu or antiflu
Antiflu is an American drug that is available in tablet form. The composition of this substance is completely identical to Theraflu. At the same time, the dosage of active ingredients in antiflu is slightly less.
Theraflu extratab contains 4 mg of chlorpheniramine, which is a synthetic derivative of pheniramine, 650 ml of paracetamol and 10 ml of phenylephrine. At the same time, in antiflu the volume of active components is 2 times lower.
In addition, the product is produced in powder form for making a medicinal drink. The quantity and set of active components in this product are identical to Theraflu Extratab.
Theraflu or Coldrex - what to choose
Coldrex or Theraflu - which is better? This question is very relevant. These substances have an identical set of active ingredients. The key difference between Coldrex Hotrem and Theraflu is the increased concentration of paracetamol and vitamin C. The volume of these substances is 750 mg and 60 mg, respectively. Coldrex also does not contain pheniramine. On sale you can find medicines with currant and lemon flavors.
Another drug from this group is Coldrex Maxgripp. It contains the maximum amount of paracetamol - 1000 mg. At the same time, the drug contains slightly less vitamin C – 40 mg. Phenylephrine is present in it in the usual volume - 10 ml.
Since this product contains a lot of paracetamol, it is very important to strictly follow the dosage. This is especially true for people with liver pathologies. The maximum permissible amount of the drug is 3-4 sachets per day.
Theraflu is a very effective remedy that helps cope with the symptoms of viral infections. If there is a need to use analogues of this drug, you should consult your doctor.
Fervex is a combination drug used in the treatment of acute respiratory diseases as a symptomatic remedy.
The active ingredients in Fervex are Paracetamol, Pheniramine, Ascorbic acid. The composition also includes auxiliary components, which include gum arabic, raspberry or lemon flavoring, sucrose, sodium saccharinate, anhydrous citric acid.
Paracetamol affects the thermoregulation center and has an antipyretic and analgesic effect. It helps reduce fever and relieve headaches, which are often a symptom of acute respiratory infections and flu.
Ascorbic acid helps strengthen the immune system and increase the body's resistance to infection. It takes part in the processes of regeneration of body tissues and carbohydrate metabolism.
Pheniramine is a histamine H1 receptor blocker - it reduces the feeling of nasal congestion, treats lacrimation, rhinorrhea, red eyes and sneezing.
Fervex effectively relieves symptoms of colds and flu, reduces fever, relieves swelling of the nasal mucosa and inflammation of the throat.
Indications for use
What does Fervex help with? According to the instructions, the drug is prescribed in the following cases:
- symptomatic treatment of acute respiratory infection of viral origin to reduce the severity of symptoms - nasal congestion, increased body temperature, aching muscles and joints.
- for the treatment of nasopharyngitis (inflammation of the mucous membrane of the nasal cavity and pharynx).
Instructions for use of Fervex, dosage
Take orally by completely dissolving the sachet in a glass (200 ml) of warm water (50–60 °C), and drink the resulting solution immediately. Best taken between meals.
The standard dosage according to the instructions for use is 1 sachet of Fervex up to 3 times a day. The interval between doses should be at least 4 hours.
In patients with impaired liver or kidney function and in elderly patients, the interval between doses of the drug should be at least 8 hours.
The duration of use without consulting a doctor is no more than 5 days when prescribed as an analgesic and no more than 3 days when prescribed as an antipyretic.
Instructions for Fervex for children
Take orally by dissolving the contents of a Fervex sachet in a glass (200 ml) of warm water.
Depending on the age of the child, the drug is used in the following doses:
- children 6–10 years old - 1 sachet 2 times a day;
- 10–12 years - 1 sachet 3 times a day;
- 12–15 years old - 1 sachet 4 times a day.
The interval between doses of the medicine should be at least 4 hours.
The duration of treatment is no more than 3 days.
Additional Information
The drug does not contain sugar, which makes it possible to prescribe it to people suffering from diabetes.
During therapy, laboratory test parameters may change when quantifying the concentration of plasma glucose and uric acid.
Fervex should not be taken simultaneously with alcohol-containing drinks.
With prolonged use of the drug in high doses, it is necessary to regularly monitor the peripheral blood picture.
Side effects
The instructions warn about the possibility of developing the following side effects when prescribing Fervex:
- From the digestive system: nausea, pain in the epigastric region; rarely – dry mouth;
- From the hematopoietic system: rarely - anemia, thrombocytopenia, methemoglobinemia.
- From the urinary system: rarely - urinary retention;
- Allergic reactions: skin rash, itching, urticaria, Quincke's edema.
- Other: rarely - accommodation paresis, drowsiness.
- With long-term use in doses significantly higher than recommended, the likelihood of liver and kidney dysfunction increases.
Contraindications
Fervex is contraindicated in the following cases:
- Erosive and ulcerative pathology of the stomach or duodenum in the acute stage.
- Portal hypertension, characterized by increased blood pressure in the vessels of the portal vein system.
- Chronic alcoholism.
- Severe renal failure.
- Deficiency of the enzyme glucose-6-phosphate dehydrogenase.
- Pregnancy (especially in the 1st and 3rd trimester), as well as lactation (breastfeeding).
- The patient's age is less than 15 years.
- Individual intolerance to paracetamol, pheniramine maleate, ascorbic acid or excipients of the drug.
The drug is used with caution in cases of concomitant liver failure, angle-closure glaucoma, congenital increases in the level of bilirubin in the blood (Gilbert, Rotor, Dubin-Johnson syndrome), hyperplasia (increase in organ volume) of the prostate gland in men, hepatitis (inflammation of the liver) viral, toxic, alcohol origin, as well as in old age.
Before starting use, it is important to make sure there are no contraindications.
Overdose
Symptoms of overdose – pale skin, loss of appetite, nausea, vomiting; hepatonecrosis (the severity of necrosis due to intoxication directly depends on the degree of overdose).
Toxic effects in adults are possible after taking more than 10-15 g of paracetamol: increased activity of “liver” transaminases, increased prothrombin time (12-48 hours after administration).
The full clinical picture of liver damage appears after 1-6 days.
Rarely, liver failure develops rapidly and can be complicated by renal failure (tubular necrosis).
In the first 6 hours after an overdose - gastric lavage, administration of SH-group donors and precursors for glutathione synthesis - methionine 8-9 hours after an overdose and N-acetylcysteine after 12 hours.
The need for additional therapeutic measures (further administration of methionine, intravenous administration of N-acetylcysteine) is determined by the concentration of paracetamol in the blood, as well as the time elapsed after its administration.
Fervex analogues, price in pharmacies
If necessary, you can replace Fervex with an analogue of the active substance - these are the following drugs:
- Flukoldin,
- Fastorik,
- Fervex for children,
- Antigrippin-Express.
When choosing analogues, it is important to understand that the instructions for use of Fervex, the price and reviews do not apply to drugs with similar effects. It is important to consult a doctor and not change the drug yourself.
Price in Russian pharmacies: Fervex powder with flavor 12.75 g 4 pcs. – from 194 to 225 rubles, 8 sachets – from 282 to 307 rubles, according to 727 pharmacies.
The shelf life is 3 years from the date of manufacture. Store in undamaged original original packaging, in a dark, dry place, out of reach of children, at an air temperature not exceeding +25° C.
What do the reviews say?
According to reviews from many people who have taken Fervex, if you take the drug at the first sign of a cold, the development of the disease can be quickly stopped. At the same time, great importance is given to bed rest, drinking plenty of fluids and proper rest - all this, together with the drug, provides good support to the body, increasing its resistance to viral infection.
Among the positive opinions there are reviews about the development of side effects. The manifestation of drowsiness, which is typical for viral infections, is especially often mentioned.
You can also find reviews that treatment with Fervex turned out to be completely useless. After therapy for several days, the cold symptoms not only did not decrease, but, on the contrary, became more complicated. In addition, inflammation in the throat, muscle aches and headaches increased.
Unfortunately, many people consider colds to be commonplace and do not make special efforts to treat them. They often try to suppress the symptoms that appear, but this approach often leads to complications, the treatment of which requires radical measures, including taking antibiotics. Therefore, if it was not possible to reduce the manifestation of a cold within 2-3 days, you need to consult a doctor.
Drug interactions
Antidepressants, antiparkinsonian drugs, antipsychotic drugs (phenothiazine derivatives) - increase the risk of side effects (urinary retention, dry mouth, constipation) of Fervex.
When used simultaneously with Fervex, GCS increases the risk of developing glaucoma.
Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites of paracetamol, which makes it possible to develop severe intoxication with a small overdose of the drug.
Inhibitors of microsomal oxidation (including cimetidine) reduce the risk of hepatotoxic action of paracetamol.
Paracetamol reduces the effectiveness of uricosuric drugs.
Ethanol contributes to the development of acute pancreatitis.
Dosage forms
powder for solution for oral administration
Manufacturers
Bristol-Myers Squibb (France), Upsa Laboratories, department of Bristol-Myers Squibb (France)
PharmGroup
Combinations of paracetamol and H1-histamine blockers
International nonproprietary name
Paracetamol+Pheniramine+Ascorbic acid
Leave procedure
Available without a prescription
Synonyms
Fervex, Fervex for children, Flukoldin
Compound
Paracetamol + Pheniramine + Ascorbic acid.
pharmachologic effect
Combined drug. Paracetamol has analgesic and antipyretic effects. Pheniramine is a blocker of H1-histamine receptors. Ascorbic acid is involved in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration, and in the synthesis of steroid hormones; reduces vascular permeability, reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid.
Indications for use
ARVI (symptomatic therapy), allergic rhinitis, nasopharyngitis; pain syndrome (mild to moderate severity).
Contraindications
Hypersensitivity, portal hypertension, alcoholism, renal failure, pregnancy (I and III trimesters), lactation, glucose-6-phosphate dehydrogenase deficiency. With caution: congenital hyperbilirubinemia, children under 6 years of age, closed-angle glaucoma, prostatic hyperplasia.
Side effect
Allergic reactions, nausea, epigastric pain, anemia, thrombocytopenia, dry mouth, accommodation paresis, urinary retention, drowsiness. With long-term use in large doses - hepatotoxic effect, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia; erosive and ulcerative lesions of the gastrointestinal tract, bleeding in the gastrointestinal tract; nephrotoxicity.
Interaction
Ethanol enhances the sedative effect of antihistamines. Antidepressants, antiparkinsonian drugs, antipsychotic drugs (phenothiazine derivatives) increase the risk of side effects (urinary retention, dry mouth, constipation). GCS increase the risk of developing glaucoma. Inducers of microsomal oxidation (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites, increasing the risk of severe intoxication with small overdoses. Microsomal oxidation inhibitors (cimetidine) reduce the risk of hepatotoxicity. Paracetamol reduces the effectiveness of uricosuric drugs.
Overdose
Symptoms: pale skin, loss of appetite, nausea, vomiting; hepatonecrosis (the severity of necrosis due to intoxication directly depends on the degree of overdose). Treatment: symptomatic. In the first 6 hours after an overdose - gastric lavage, administration of SH-group donors and precursors for the synthesis of glutathione - methionine 8-9 hours after the overdose and N-acetylcysteine after 12 hours.
Directions for use and dosage
Children (children's dosage form) 6-10 years old - 1 sachet 2 times a day, 10-12 years old - 1 sachet 3 times a day, 12-15 years old - 1 sachet 4 times a day. The interval between doses is at least 4 hours.
special instructions
For hyperthermia lasting more than 3 days and pain for more than 5 days, a doctor’s consultation is required. Distorts laboratory test results in the quantitative determination of glucose and uric acid in plasma. During treatment, monitoring of the peripheral blood picture and the functional state of the liver is necessary. During the treatment period, it is necessary to refrain from drinking ethanol, driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Storage conditions
Store in a dry place, at a temperature not exceeding 25 degrees. WITH.
AND pheniramine maleate.
Additional ingredients: sucrose, acacia gum, citric acid, raspberry flavor and sodium saccharinate.
Release form
Fervex is produced in the form of a powder, packaged in sachets of 13.1 and 4.95 g, 8 pieces per pack.
A special form is also available - Fervex for children, which is packaged in 3 g bags, 8 pieces per pack.
pharmachologic effect
This drug has antihistamine, analgesic And antipyretic action.
Pharmacodynamics and pharmacokinetics
The effect of this combination drug is determined by the components that are present in its composition.
Paracetamol capable of manifesting analgesic And antipyretic effect by influencing central thermoregulation in the hypothalamus. At the same time, the body temperature also decreases and other pain sensations are eliminated.
Ascorbic acid is one of the regulators of redox processes, tissue regeneration, GCS production, coagulation, carbohydrate metabolism, procollagen and helps normalize capillary permeability. The use of this vitamin increases the body's resistance by stimulating the immune system.
Substance pheniramine refers to H1-histamine receptor blockers. With its help, the manifestations of rhinorrhea, sensations of nasal congestion, lacrimation, sneezing, redness and eyes are reduced.
Inside the body, the drug undergoes rapid and complete absorption. Its maximum concentration in plasma is detected 30-60 minutes after application. Good distribution in tissues and physiological fluids, but also penetration through the BBB was noted. The connection with plasma proteins is completely insignificant. carried out in the liver, resulting in the formation of inactive. The components of Fervex are excreted through the kidneys.
Indications for use of Fervex
Main indications for use:
- carrying out symptomatic treatment ;
Contraindications
Contraindications to the use of Fervex:
- sensitivity to the drug;
- erosions and ulcers of the gastrointestinal tract;
- portal hypertension;
- deficiency of the enzyme glucose-6-phosphate dehydrogenase;
- age up to 15 years;
- , .
Fervex for children is contraindicated for:
- sensitivity to it;
- severe liver and kidney disorders;
- deficiency of the enzyme glucose-6-phosphate dehydrogenase;
- blood diseases;
- children under 6 years of age.
Reception with maximum caution is allowed when benign hyperbilirubinemia, .
Side effects
Instructions for use of Fervex (Method and dosage)
This drug is intended for oral administration. First, the contents of the sachet are completely dissolved in a glass of water and immediately drunk. The optimal time to take it is between meals.
The course of treatment is no more than 5 days.
Instructions for use of Fervex for children also recommend taking it orally, after thoroughly dissolving the powder in 200 ml of water.
In this case, children's Fervex is prescribed taking into account the age of the small patient. Therefore, Fervex for children 6-10 years old is recommended in a daily dosage of 1 sachet for 2 doses. At the age of 10-12 years you can take one sachet 3 times a day, and at 12-15 years old - one sachet up to 4 times a day.
The instructions for children advise maintaining an interval of 4 hours between doses. The duration of therapy is no more than 3 days.
Overdose
When taking Fervex for a long time at an increased dosage, symptoms such as pale skin, decreased blood pressure, hepatonecrosis, nausea, and vomiting may appear. In rare cases, it may occur liver failure .
Treatment includes mandatory measures in such cases: gastric lavage, use of SH-group donors or precursors for the production of glutathione-methionine 8-9 hours after the overdose. If the overdose period is 12 hours, then N-acetylcysteine is administered. At the same time, other accompanying measures are carried out, which depend on the symptoms that appear.
Interaction
Combination with antidepressants, antiparkinsonian and antipsychotic drugs may increase the risk of side effects.
Simultaneous use with inducers of microsomal oxidation in the liver area, for example, with , barbiturates, And tricyclic antidepressants can increase the production of hydroxylated active metabolites, as a result of which the development of severe symptoms is possible.
special instructions
Taking this drug may cause distortion in laboratory parameters when determining the concentration glucose And uric acid . Patients suffering from or adhering to it should take into account that the water sachet contains sugar in the amount of 11.5 g or 0.9 XE.
Terms of sale
Over the counter.
Storage conditions
This powder should be stored in a dry and cool place, away from children.
Best before date
Fervex during pregnancy
It has been established that during pregnancy this drug can only be used in the second trimester. The first and third trimester are a contraindication for use.
It is prohibited to take Fervex while breastfeeding.
Fervex's analogues
Level 4 ATX code matches:Which is better – Fervex or Theraflu?
Each of these drugs has a similar composition and indications for use. However, it contains less paracetamol, but its effect is not reduced.
In this case, the antipyretic and analgesic effect manifests itself almost equally.
Alcohol
The combination of paracetamol and alcohol can cause toxic damage to the liver, leading to the development alcoholic hepatosis And acute . Therefore, it is better to refrain from using alcohol-containing products.
Reviews about Fervex
There are a lot of reviews about Fervex on medical forums. According to users, if you take this drug at the first sign of a cold, the development of the disease can be quickly stopped. At the same time, great importance is given to bed rest, drinking plenty of fluids and proper rest - all this, together with the drug, provides good support to the body, increasing its resistance to viral infection.
Users often discuss Fervex for children, which can be taken by young patients from 6 years of age. At this age, it is difficult for children to give pills, but they take drugs in the form of suspensions, sweet solutions and syrups more willingly. The effectiveness of this drug is also maximal when it is started when the first symptoms of the disease appear.
Among the positive opinions, there are reviews of Fervex that report the development of side effects. The manifestation is especially often mentioned, which, however, is also typical for viral infections.
You can also find reports that treatment with this drug turned out to be completely useless. After therapy for several days, the cold symptoms not only did not decrease, but, on the contrary, became more complicated. In addition, inflammation in the throat, muscle aches and headaches increased.
Unfortunately, many people consider colds to be commonplace and do not make special efforts to treat them. They often try to suppress the symptoms that appear, but this approach often leads to complications, the treatment of which requires radical measures, including taking.
Therefore, if it was not possible to reduce the manifestation of a cold within 2-3 days, you need to consult a doctor. The specialist will prescribe appropriate medications and additional examination, which will help to achieve a quick recovery.
Fervex price, where to buy
The price of Fervex for children starts from 250 rubles.
The price of Fervex (1 sachet) varies between 25-35 rubles.
- Online pharmacies in Russia Russia
- Online pharmacies in Ukraine Ukraine
- Online pharmacies in Kazakhstan Kazakhstan
ZdravCity
Fervex lemon with sugar 13.1g 8 pcs.Bristol-Myers Squibb/UPSA SAS
Fervex lemon without sugar for cooking. sol. for internal reception 12 pcs. UPSA SAS
Fervex lemon without sugar for cooking. sol. for internal reception 4 pcs. UPSA SAS
Fervex limnon with sugar for cooking. sol. for internal reception 4 pcs. UPSA SAS